Posaconazole Impurity 123

Posaconazole Impurity 123 - Names and Identifiers

Name	[(2S)-2-(phenylmethoxy)propylidene]-Hydrazinecarboxaldehyde
Synonyms	Posaconazole Impurity 123 (S)-N'-(2-(benzyloxy)propylidene)formylhydrazide (S,E)-N'-(2-(benzyloxy)propylidene)formohydrazide Formic acid (2 (S)-benzyloxy-propylidene)-hydrazide (S)-[2-(Benzyloxy)propylidene]hydrazinecarboxaldehyde [(2S)-2-(PhenylMethoxy)propylidene]hydrazinecarboxaldehyde [(2S)-2-(phenylmethoxy)propylidene]-Hydrazinecarboxaldehyde 2-[(2S)-2-(Phenylmethoxy)propylidene]hydrazinecarboxaldehyde Hydrazinecarboxaldehyde, 2-[(2S)-2-(phenylmethoxy)propylidene]-
CAS	170985-84-9

Posaconazole Impurity 123 - Physico-chemical Properties

Molecular Formula	C11H14N2O2
Molar Mass	206.24
Density	1.06±0.1 g/cm3(Predicted)
Boling Point	313.2±44.0 °C(Predicted)
Solubility	Chloroform, Dichloromethane
Appearance	Solid
Color	Pale Yellow
pKa	13.58±0.23(Predicted)
Storage Condition	Room Temprature

Posaconazole Impurity 123 - Introduction

[(2S)-2-(phenylmethoxy)propylidene]-Hydrazinecarboxaldehyde is an organic compound with the following properties and uses:

Nature:
-Appearance: Colorless or light yellow liquid.
-Molecular formula: C11H16N2O2
-Molecular Weight: 212.26
-Melting point:-10 ℃
-Boiling point: 234 ℃
-Density: 1.10 g/mL

Use:
[(2S)-2-(phenylmethoxy)propylidene]-Hydrazinecarboxaldehyde is commonly used in the field of organic chemical synthesis. It is an intermediate for the synthesis of other organic compounds and is commonly used in the synthesis of drugs, coatings and other compounds.

Method:
A common method for preparing [(2S)-2-(phenylmethoxy)propylidene]-Hydrazinecarboxaldehyde is:
First, condensing 2-(benzyloxy) propanol with hydrazine to obtain 2-(benzyloxy) propyl hydrazine;
Then, 2-(benzyloxy) propyl hydrazine is reacted with formaldehyde to generate [(2S)-2-(phenylmethoxy)propylidene]-Hydrazinecarboxaldehyde through reduction and dehydration.

Safety Information:
- [(2S)-2-(phenylmethoxy)propylidene]-Hydrazinecarboxaldehyde may be irritating to the eyes, skin and respiratory tract and should be avoided.
-Wear protective goggles, protective gloves and a suitable protective mask during use or operation.
-Keep it airtight during storage, away from fire and oxidizing agents, and avoid exposure to direct sunlight.
-If taken by mistake or inhaled, seek medical attention immediately and show your safety data sheet to your doctor.

Last Update：2024-04-09 21:01:54